70Y/F WITH C/O LOOSE STOOLS AND LOW BACK ACHE

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70Y/F WITH C/O LOOSE STOOLS AND LOW BACK ACHE
A 70yr old female came with c/o loose stools since 10days 
vomitings 10 days ago (2episodes)
C/o low back ache
C/o blebs over Rt lower limb a/w Swelling 
since 20 days
Pt was apparently asymptomatic 15yrs back
15 yrs back-  H/o fever- on checkup found to be Hypertensive
10yrs ago-  C/o joint pains- initially in distal small joints then to elbow and now multiple joints are involved (pt doesn't remember the sequence of involvement of joints after that)
8yrs back- joint pains aggravated for which she started on Tab.ACECLOFENAC, Tab.OMNACORTIL 5mg OD - using daily- tappered in between but as she developed joint pains again she restarted Tab.Omnacortil 5mg OD.
4yrs ago- underwent tooth extraction
H/o slip and fall- operated for Rt tibial # (implant insitu)
3yrs ago- H/o fever,was admitted in our hospital was told to have some renal problem (no records available) later was discharged ?UTI ?PYELONEPHRITIS 
1yr ago- C/o facial puffiness,generalized weakness, on and off B/l pedal edema, still having multiple joint pains
5months back- C/o Rt DIP,PIP,wrist joint pain with restriction of movements 
10 days ago- C/o blebs over dorsal aspect of Rt foot later formed scab a/w swelling of Rt lower limb which regressed now 
C/o low back ache a/w 5-6 episodes of loose stools/day ,large volume, watery consistency 
H/o 2 episodes of vomitings 10 days ago not a/w pain abdomen,fever, burning micturation, cough,sob
No C/o chest pain,palpitations, giddiness,sweating 
Bowel and Bladder movements-regular
K/c/o HTN since 15 yrs, on T.TELMA H (80/12.5) OD
H/o chronic NSAID abuse, steroid abuse for multiple joint pains 
N/k/c/o DM,CVA
H/o reduced appetite since 1yr
Menopause at 40yrs ago
Vitals @ admission :
Temp-96.6 F
PR-110 bpm
BP-100/70 mmHg (not on antiHTN since 4 days)
RR-16/min
SPO2- 98@RA
GRBS- 87mg/dl
On examination:
No pallor/Icterus/cyanosis/clubbing/Generalized lymphadenopathy 
Pedal edema +
Cushingoid appearance of face, dry skin, no purple appearance of striae
L/E :
Rt DIP, PIP and wrist - tenderness +, painful ROM+
Rt and Lt elbow - normal 
B/L shoulders - pain on movement 
Lower limbs-
Rt LL- Rt knee deformity +, Rt ankle externally rotated 
Lt LL- normal, no ROM
S/E:
CVS- S1 S2 heard, no murmurs 
R/S- BAE+
P/A- soft, nontender,BS +
CNS- 
conscious
Cranial nerves- intact
Sensory system- normal
Motor system- normal
Reflexes
                     Rt       Lt
Biceps         3+      2+
Triceps        3+     1+
Supinator    2+      1+
Knee             -          -
Ankle            -          -
Plantar     withdrawal  withdrawal 
Provisional diagnosis-
1. ACUTE GASTROENTERITIS (?Small bowel)
2. ASSYMETRIC POLYARTHRITIS 
3. ?IATROGENIC CUSHINGS
4. ANEMIA UNDER EVALUATION (? IDA,? Anemia of Chronic diarrhea)
5. ?AKI on ?CKD (secondary to NSAID abuse)
Investigations
USG Abdomen and PelvisECGCXRXray LS SPINEXray wrist- AP and lateral view
Treatment:
1) IVF - 2 NS, 2 RL @100ml/hr
2)ORS sachet in 1 lit of water-200ml after each stool
3)Tab.PREDNISOLONE 5mg PO OD
4)Tab.ULTRACET 1/2 tab QID

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